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Ingredient

Tretinoin

Tretinoin (all-trans retinoic acid) is a prescription-strength retinoid used for acne and photoageing. It is not sold OTC in most countries.

Also known as: All-trans retinoic acid

INCI: Tretinoin

Part of: Retinoids

How it works

It increases cell turnover and is used for acne, texture and sometimes post-acne marks under medical supervision.

How people use it

  • Prescribed strength and frequency vary (often 0.025–0.1%)
  • Usually evening application with moisturiser
  • May appear in personalised online formulas after consultation
  • Started slowly to limit irritation

Who it may suit

May suit

  • Persistent acne when OTC options are not enough
  • People under dermatology or GP care
  • Combination formulas tailored by a clinician

May want something else if

  • Self-selection without a prescription where required
  • Pregnancy without explicit medical guidance

What to watch for

  • Significant dryness and peeling possible
  • Daily SPF is essential
  • Only use as directed by your prescriber

Compare alternatives

Compared with adapalene for tolerability, or azelaic acid in combination prescriptions.

View comparisons

AcneSpot picks

Shortlists that include products with Tretinoin.

Products with Tretinoin